Characterization of Isup ?2 Prostate Cancer At Multiparametric MRI: Development and Assessment of The Accuracy of A Zone-Specific Computer-Aided Diagnosis System in An External Dataset
Tristan Jaouen, Rйmi Souchon, Olivier Rouviиre, Florian Di Franco, Au Hoang Dinh, Audrey Duran, Paul-Cezar Moldovan, Flavie Bratan, Alain Ruffion, Marc Colombel, Sйbastien Crouzet, Christelle Gonindard-Melodelima
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Multi-parametric magnetic resonance (MR) imaging is now recommended prior to prostate biopsies. However, the examination has poor specificity and lacks inter-reader reproducibility. To help radiologists, we developped a zone-specific computer-aided diagnostic (CAD) system based on quantitative imaging. The CAD performed well in an external cohort of patients referred for prostate biopsy and imaged on a MR scanner that was not involved in the training. It provided robust results similar to those of specialized uro-radiologists.